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While melatonin may be most well-known for promoting sleep,11 it appears to improve age-related skin elasticity and tone when used topically,12 as well as slowing age-related cardiovascular and neurodegenerative conditions in animal studies.13 2010 Supplemental pyrroloquinoline quinone (PQQ), a compound that promotes the growth of new mitochondria, was suggested as a way to rejuvenate aging cells by Life Extension

Additionally, circadian disruption might promote neurodegenerative processes implicated in AD development, as indicated by recent animal studies

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